Normal neurological outcome after congenital thyrotoxicosis: prognostic value of observation of general movements.

We followed up a patient born preterm with congenital thyrotoxicosis by observing her general movements (GMs) in accordance with Prechtl's method. Initially a chaotic pattern was observed. Along with the normalization of thyroid hormones, the GM pattern changed to a poor repertoire at four weeks of life, full-blown writhing movements at six weeks and fidgety movements at the age of four months. This is the first report of chaotic GMs in a neonate reflecting transient neurological dysfunction related to congenital thyrotoxicosis, with subsequent normal neurological and cognitive outcome.

Control de calidad de un programa de detección, diagnóstico e intervención precoz de la hipoacusia en recién nacidos. Documento oficial de la comisión para la Detección de la Hipoacusia en Recién Nacidos (CODEPEH) / Quality control of an early detection, diagnosis and early intervention program for deafness in newborn. Official document of the Early Detection Comission of Deafness in Newborn (CODEPEH)

No disponible

No disponible

Linfangioma de pared torácica. A propósito de un caso / No disponible

El linfangioma es una malformación congénita derivada de los vasos linfáticos y localizada generalmente en la cabeza o en el cuello. La ecografía es útil para orientar el diagnóstico. El tratamiento de elección es la cirugía, siempre que no sea mutilante. Existen otras alternativas terapéuticas como la inyección intralesional de agentes esclerosantes como el OK-432 que es seguro y muchas veces eficaz. Presentamos el caso de un linfangioma de pared torácica en un niño cuya resolución aconteció después de la punción-aspiración realizada al diagnóstico (AU)

Lymphangioma is a benign, congenital type of tumor, derived from lymphatic vessels, and located generally in head and neck. Ultrasonography is the procedure of choice for establishing the diagnosis. The main treatment modality is surgical excision, if it is not mutilating. Intralesional injection OK-432 represents an alternative, safe and effective treatment for lymphangiomas. We present a case of lymphangioma on the thoracic wall, solved after the punction (AU)

[The pediatric heart transplant. Its evolution and early postoperative complications]. / Trasplante cardíaco pediátrico. Evolución y complicaciones postoperatorias tempranas.

BACKGROUND: Cardiac transplantation is an acceptable therapeutic alternative for cardiac diseases refractory to other forms of management in adults as well as in infants and children. METHODS: Between 1987-1992 7 children (4 girls and 3 boys) underwent cardiac transplantation: four with dilated cardiomyopathy, one with cardiac fibroma and two with hypertrophic cardiomyopathy. Age at transplantation ranged from 2 months to 13 years and 5 months, with a follow-up ranging from 15 months to 5 years and 9 months. Prophylaxis of acute rejection consisted of cyclosporine, azathioprine and glucocorticoids. RESULTS: Two patients presented acute rejection three weeks after cardiac transplantation, with a good response to high dose glucocorticoids. Two patients developed severe infection (sepsis by Staphylococcus aureus) with successful outcome after antibiotic treatment. One patient died in the early postoperative period and other after 4 years 11 months postransplantation because myelodysplastic syndrome. At present only one case is receiving glucocorticoids in immunoprophylaxis. The status is asymptomatic in the other 5 patients with a normal height-weight development. CONCLUSIONS: Heart transplantation provides durable therapy for congenital and myopathic heart disease in infants and children with an excellent quality of life.

Use of recombinant human granulocyte-macrophage colony stimulating factor in an infant with reticular dysgenesis.

We present the case of a 2-month-old infant with reticular dysgenesis who was treated with recombinant granulocyte-macrophage colony stimulating factor with the aim of stimulating granulopoiesis while awaiting bone marrow transplant.

Giant jejunoileal duplication: prenatal diagnosis and complete excision without intestinal resection.

A 7-week-old child presented to the pediatrician after persistent vomiting and abdominal distension developed. Intestinal dilatation had been detected in utero. Emergency ultrasonography showed only small bowel dilatation. There were no signs of intestinal obstruction; however, complete intestinal malrotation was demonstrated by an upper gastrointestinal series and barium enema. Intestinal duplication was also suspected, and emergency laparotomy was performed. A 70-cm-long jejunoileal duplication was found and successfully dissected free from the normal small bowel and excised without intestinal resection-anastomosis. The authors describe this unique case and the surgical technique for the treatment of small bowel duplications.

Prostaglandins in human milk.

Human milk contains many different components which interact locally in the gastrointestinal tract and stimulate some systemic functions. Among these substances are prostaglandins. We obtained samples of foremilk and hindmilk in 8 lactating women by manual expression before and after 9 a.m. and 9 p.m. on the 3rd day post partum. The following values were found for prostaglandin E2: foremilk, 162 +/- 135 pg/ml; hindmilk, 198 +/- 148 pg/ml. The values for 6-ketoprostaglandin F1 alpha were: foremilk, 818 +/- 386 pg/ml, and hindmilk, 795 +/- 487 pg/ml. The values for thromboxane B2 were: foremilk, 3,557 +/- 2,770 pg/ml and hindmilk, 4,476 +/- 4,053 pg/ml. The results showed a great variability without statistical differences between paired values of the four groups. This dispersion may be produced by the procedure for extraction and by individual basal levels.